Elidel Side Effects Lawsuit
Elidel, a pimecrolimus cream, is used as the second-line therapy, in non- immunocompromised adults and children 2 years of age and older, for short-term and non-continuous chronic treatment of mild to moderate atopic dermatitis in patients who have failed to respond adequately to other topical prescription treatments or when other topical prescription treatments are not advisable.
Elidel is available in a 30 gram tube, a 60 gram tube, and a 100 gram tube and the cream contains the immunosuppressant 33-epi-chloro-derivative of the macrolactam ascomycin called pimecrolimus. 10mg of pimecrolimus is contained in each gram of Elidel Cream 1%. The pimecrolimus is contained in a whitish cream base of cetyl alcohol, benzyl alcohol, citric acid, oleyl alcohol, propylene glycol, sodium cetostearyl sulphate, mono-glycerides, di-glycerides, sodium hydroxide, stearyl alcohol, triglycerides, and water. The cream should be stored at 77°F and the excursions are permitted to 59°F-86°F. The cream is not to be frozen.
The compound pimecrolimus is a fine crystalline, white to off-white powder that is soluble in methanol and ethanol but is not soluble in water. It has a molecular weight of 810.47 and is chemically (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-12-[(1E)-2-{(1R,3R,4S)-4-chloro- 3-methoxycyclohexyl}-1-methylvinyl]-17-ethyl-1,14-dihydroxy-23,25-dimethoxy- 13,19,21,27-tetramethyl-11,28-dioxa-4-aza-tricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16- tetraone. The empirical formula for the compound is C43H68CINO11.
Elidel Side Effects Lawsuit